2010
Naturally Occurring Osmolytes Modulate the Nano-Mechanical Properties of Polycystic Kidney Disease (PKD) Domains
L Ma, M Xu, and AF Oberhauser
J Bio Chem. Publiches online October 11, 2010. PubMed Link
Water Prescription in Autosomal Dominant Polycystic Kidney Disease: A Pilot Study
CJ Wang, C Creed, FT Winklhofer, and JJ Grantham
Clin J Am Soc Nephrol 5. Published online September 28, 2010. PubMed Link
Evaluation and Management of Pain in Autosomal Dominant Polycystic Kidney Disease
MC Hogan and SM Norby
Advances in Chronic Kidney Disease, Vol 17, No 3 (May), 2010: pp e1-e16. PubMed Link
Randomized Clinical Trial of Long-Acting Somatostatin for Autosomal Dominant Polycystic Kidney and Liver Disease
MC Hogan, TV Masyuk, LJ Page, VJ Kubly, EJ Bergstralh, X Li, B Kim, BF King, J Glockner, DR Holmes III, S Rossetti, PC Harris, NF LaRusso, and VE Torres
J Am Soc Nephrol 2010 Jun;21(6):1052-61. Epub 2010 Apr 29. PubMed Link
Sirolimus Therapy to Halt the Progression of ADPKD
N Perico, L Antiga, A Caroli, P Ruggenenti, G Fasolini, M Cafaro, P Ondei, N Rubis, O Diadei, G Gherardi, S Prandini, A Panozo, RF Bravo, S Carminati, FR Leon, F Gaspari, M Cortinovis, N Motterlini, B Ene-Iordache, A Remuzzi and G Remuzzi
J Am Soc Nephrol. Published online May, 2010. PubMed Link
Molecular diagnostics for ADPKD
PC Harris and S Rossetti
S. Nat. Rev. Nephrol. Published online February, 2010. PubMed Link
A Pilot Clinical Study to Evaluate Changes in Urine Osmolatity and Urine cAMP in Response to Acute and Chronic Water Loading in ADPKD
I Barash, MP Ponda, DS Goldfarb, and EY Skolnik
Clin J Am Soc Nephrol 2010. Published online February, 2010. PubMed Link
Imaging for the prognosis of ADPKD
KT Bae and JJ Grantham
Nat. Rev. Nephrol. 2010. 6: 96-106. PubMed Link
Glomerulocystic kidney disease.
JJ Bissler, BJ Siroky, and H Yin
Pediatr Nephrol 2010. Published online January, 2010. PubMed Link
Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1
JM Shillingford, KB Piontek, GG Germino, and T Weimbs
J Am Soc Nephrol 2010. Published online January, 2010. PubMed Link
The HALT Polycystic Kidney Disease Trials: Design and Implementation
AB Chapman, VE Torres, RD Perrone, TI Steinman, KT Bae, JP Miller, DC Miskulin, FR Oskoui, A Masoumi, MC Hogan, FT Winklhofer, W Braun, PA Thompson, CM Myers, C Kelleher, and R W Schrier
Clin J Am Soc Nephrol 2010. 5. 102-109. PubMed Link
2009
Chemical Modifier Screen Identifies HDAC Inhibitors as Suppressors of PKD Models
Y Cao, N Semanchik, SH Lee, S Somlo, PE Barbano, R Coifman and Z Sun
PNAS published 4 December 2009, 10.1073/pnas.0911987106. PubMed Link
Renal Primary Cilia Lengthen after Acute Tubular Necrosis
E Verghese, SD Ricardo, R Weidenfeld, J Zhuang, PA Hill, RG Langham and JA Deane
J AM Soc Nephrol 2009. 20: 2147-2153. PubMed Link
The Role of the Mammalian Target of Rapamycin (mTOR) in Renal Disease
W Lieberthal and JS Levine
J AM Soc Nephrol 2009. Published online November, 2009. PubMed Link
Identification of a unique urinary biomarker profile in patients with ADPKD
A Kistler, H Mischak, M Danka, RP Wuthrich and AL Serra
Kidney Int 2009. 76(1): 89-96. PubMed Link
Renal Volume, Renin-Angiotensin-Aldosterone System, Hypertension, and Left Ventricular Hypertrophy in Patients with ADPKD
RW Schrier
J AM Soc Nephrol 2009. 20: 1888-1893. PubMed Link
Characterization of PKD Protein-Positive Exosome-Like Vesicles
MC Hogan, L Manganelli, JR Woollard, AI Masyuk, TV Masyuk, R Tammachote, BQ Huang, AA Leontovich, TG Beito, BJ Madden, MC Charlesworth, VE Torres, NF Russo, PC Harris, and CJ Ward
J AM Soc Nephrol 2009. 20: 278-88. PubMed Link
The cAMP Effectors Epac and Protein Kinase A(PKA) are Involved in the Hepatic Cystogenesis of an Animal Model of ARPKD
JM Banales, TV Masyuk, SA Gradilone, AI Masyuk, JF Medina, and NF La Russo
Hepatology 2009. 49: 160-174. PubMed Link
Family History of Renal Disease Severity Predicts the Mutated Gene in ADPKD
M Barua, O Cil, AD Paterson, K Wang, N He, E Dicks, P Parfrey and Y Pei
J Am Soc Nephrol 2009. 20. 1833-1838. PubMed Link
Steriod-free maintenance immunosuppression in kidney transplantation: is it time to consider it as a standard therapy?
FL Luan, DE Steffick and AO Ojo
Kidney International 2009. 1-6. e-published July 2009. PubMed Link
Cutaneous Microcirculation Is Impaired in Early Autosomal Dominant Polycystic Kidney Disease
A Ramunni, P Bresica, D Quaranta, MS Bianco, P Ranieri, E Dolce and P Coratelli
Nephrol Clin Pract 2009. 113: c71-c75. PubMed Link
Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD)
I Zafar, FA Belibi, Z He and CL Edelstein
Nephrol Dial Transplant 2009. 24: 2349-2353. PubMed Link
Early renal and vascular changes in ADPKD patients with low-grade albumin excretion and normal renal function
PJ Azurmendi, AR Fraga, FM Galan, C Kotliar, EE Arrizurieta, MG Valdez, PJ Forcada, JS Santelha Stefan and RS Martin
Nephrol Dial Transplant 2009. 24: 2458-2463. PubMed Link
Polycystic Liver Disease
T Schnelldorfer, VE Torres, S Sakaria, CB Rosen and DM Nagorney
Ann Surg 2009. 250: 112-119. PubMed Link
PPARgamma agonists inhibit vasopressin-mediated anion transport in the MDCK-C7 cell line
C Nofziger, KK Brown, CD Smith, W Harrington, D Murray, J Bisi, TT Ashton, FP Maurio, K Kalsi, TA West, D Baines, and BL Blazer-Yost
Am J Physiol Renal Physiol 2009. 297: F55-F62. PubMed Link
Renal injury is a third hit promoting rapid development of adult polycystic kidney disease
A Takakura, L Contrino, X Zhou, JV Bonventre, Y Sun, BD Humphreys, and J Zhou
Human Molecular Genetics 2009. 18(14):2523-2531. PubMed Link
2008 Homer W. Smith Award: Insights into the Pathogenesis of Polycystic Kidney Disease from Gene Discovery
PC Harris
J Am Soc Nephrol 2009. 20: 1188-1198. PubMed Link
Safety and tolerability of sirolimus treatment in patients with ADPKD
AL Serra, AD Kistler, D Poster, F Krauer, O Senn, S Raina, I Pavik, K Rentsch, A Regeniter, D Weishaupt and RP Wuthrich
Nephrol Dial Transplant 2009. 1-9. e-published June, 2009. PubMed Link
A Case for Water in the Treatment of Polycystic Kidney Disease
V Torres, L Bankir and JJ Grantham
Clin J Am Soc Nephrol 2009. 4: 1140-1150, e-published 2009. PubMed Link
Quality of Life in Autosomal Dominant Polycystic Kidney disease Patients not yet on Dialysis
D Rizk, C Jurkovits, E Veledar, S Bagby, DA Baumgarten, F Rahbari-Oskoui, T Steinman and AB Chapman
Clin J Am Soc Nephrol 2009. 4: 560-566. PubMed Link
The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway
TR Hartman, D Liu, JT Zilfou, V Robb, T Morrison, T Watnick, and EP Henske
Hum Mol Genet. January 2009. 18(1): 151-163. e-published October, 2008. PubMed Link
TRPP2 channels regulate apoptosis through the Ca2plus concentration in the endoplasmic reticulum
T Wegierski, D Steffil, C Kopp, R Tauber, B Buchholz, R Nitschke, EW Kuehn, G Walz, and M Kottgen
The EMBO Journal. (2009). 1-10. PubMed Link
DNA Testing for Live Kidney Donors at Risk for Autosomal Dominant Polycystic Kidney Disease
E Huang, M Samaniego-Picota, T McCune, JK Melancon, RA Montgomery, R Ugarte, E Kraus, Karl Womer, H Rabb and T Watnick
Transplantation 2009. 87: 133-137. PubMed Link
MRI-based Kidney volume Measurements in ADPKD: Reliability and Effect of Gadolinium Enhancement
KT Bae, C Tao, F Zhu, JE Bost, AB Chapman, JJ Grantham, VE Torres, LM Guay-Woodford, CM Meyers, WM Bennett and Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP)
Clin J AM Soc Nephrol 2009. 4: 719-725. PubMed Link
Prospective Change in Renal Volume and Function in Children with ADPKD
MA Cadnapaphornchai, K McFann, JD Strain, A Masoumi, and RW Schrier
Clin J AM Soc Nephrol 2009. 4: 820-829. PubMed Link
Evaluation of Nephrolithiasis in Autosomal Dominant Polycystic Kidney Disease Patients
JL Nishiura, RFCA Neves, SRM Eloi, SMLF Cintra, SA Ajzen and IP Heilberg
Clin J AM Soc Nephrol 2009. 4: 838-844. PubMed Link
Cardiovascular Abnormalities in Autosomal Dominant Polycystic Kidney Disease
T Ecder and RW Schrier
Nat. Rev. Nephrol. (2009) 5: 221-228. PubMed Link
Verification of Consumers’ Experiences and Perceptions of Genetic Discrimination and its impact on Utilization of Genetic Testing
K Barlow-Stewart, SD Taylor, SA Treloar, M Stranger and M Otlowski
Genet Med. 2009. 11(3):193-201. PubMed Link
2006
Volume Progression in ADPKD: The Major Factor Determining Clinical Outcomes
JJ Grantham, AB Chapman and VE Torres
Clin J Am Soc Nephrol 2006. 1: 148-157. PubMed Link