Clinical studies

For drugs and therapies to be developed for PKD, clinical studies must be conducted. Patients play a key role in the research and development process by volunteering to participate in clinical studies. From observational studies to clinical trials, you can help researchers unlock the secrets of PKD and find a treatment by participating in a study.

Study Title
A New Diet for Patients with Autosomal Dominant Polycystic Kidney Disease Info
A Safety, Pharmacokinetic and Dose-Escalation Study of KD019 in Subjects With ADPKD Info
A Study to Investigate the Long-term Safety and Efficacy of Tolvaptan in Patients with ADPKD (Extension of Trial 156-04-251) Info
ADPKD Pain Study Info
Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease Info
Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to ADPKD (REPRISE) Info
Lanreotide in Polycystic Kidney Disease Study (LIPS) Info
Mesenchymal Stem Cell Transplantation in Patients with Chronic Renal Failure Due to Polycystic Kidney Disease (PKD) Info
Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease (TAME) Info
Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Info
Open-Label Tolvaptan Study in Subjects With ADPKD (TEMPO 4/4) Info
Open-label Trial to Evaluate the Long Term Safety of Titrated Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease Info
Pasireotide LAR in Severe Polycystic Liver Disease (SOM230) Info
Pilot Study of Niacinamide (Vitamin B3) in Polycystic Kidney Disease (NIAC-PKD2) Info
Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease - The Vienna RAP Study Info
Radiofrequency Ablation for ADPKD Blood Pressure and Disease Progression Control (RAFALE) Info
Renal Sympathetic Denervation for Reduction of Pain and Improvement of Insulin Sensitivity in Adult Polycystic Kidney Disease Info
Sirolimus for Massive Polycystic Liver (SILVER) Info
Somatostatin in Patients with ADPKD and Moderate to Severe Renal Insufficiency (ALADIN 2) Info
Study of Lanreotide to Treat Polycystic Kidney Disease (DIPAK1) Info
The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease (PKD) Transplanted Recipients (EVERKYSTE) Info
Triptolide-Containing Formulation as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD) Info
Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide (Vitamin B3) in Polycystic Kidney Disease (NIAC-PKD1) Info
Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease (CURSOR) Info
Use of Low Dose Pioglitazone to Treat Autosomal Dominant Polycystic Kidney Disease (PIOPKD) Info

All about clinical studies

PKD Clinical Studies Fast Draw

This video describes the role of clinical trials in achieving FDA approval for drug treatments.

Participate in clinical studies to discover PKD treatments and improve your health

For drugs and therapies to be developed for PKD, clinical studies must be conducted. Patients play a key part. Learn how you can help unlock the secrets of PKD and find a treatment by participating in a study.

Know what’s happening with
Alerts and updates

One of the largest impediments to clinical trial patient participation begins with awareness. We believed it was our goal to address this challenge and launched the Clinical Trials Awareness Program (CTAP), an aggressive program to increase awareness of PKD clinical studies among patients and families. The goal is to simplify the process of finding clinical studies for PKD patients in their geographic area by sending Accelerating Clinical Trials (ACT) alert emails about studies that are being conducted.