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    The sequence of drug development webinar
    7 p.m. CST, Dec. 2

    Ever wonder why it takes so long to find a drug therapy? Join us as our Chief Scientific Officer, David Baron, Ph.D., explains the process as it relates to PKD. Register now

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PKD News

PKD Foundation helps fund ASN Foundation for Kidney Research Fellowship Program and Jared J. Grantham Fellowship

Dr. Jared GranthamThe PKD Foundation has entered a new partnership that will attract more early-career scientists to PKD. A contribution of $500,000 to the American Society of Nephrology (ASN) Foundation for Kidney Research will help fund future generations of nephrology researchers through their fellowship program. A $1.5 million match by ASN will make this investment go even further. The $2 million will fund the Jared J. Grantham Research Fellowship, named after the PKD Foundation's co-founder.

Because of the PKD Foundation's support, the ASN Foundation has fully endowed their program, which means they can continuously fund researchers into the future. The ASN Foundation has committed $20 million to fund 10 new and 10 continuing fellowships annually. Recipients receive $100,000 over two years to conduct research for patients with kidney diseases such as PKD.

Jackie Hancock, Jr., PKD Foundation CEO, is appreciative of ASN and the ASN Foundation for Kidney Research for this unique opportunity. "As an organization that is funded completely by donors, multiplying the PKD Foundation's contribution through this 3:1 match is significant and allows donor dollars to go even further."

In addition to the financial aspect, this partnership will:

  • Heighten the PKD Foundation's profile in the research community
  • Strengthen the PKD Foundation's investment in science by helping to:
    • Provide a broader reach
    • Attract new PKD researchers
    • Deliver ongoing support for PKD scientists 

"The PKD Foundation believes that fellowships are a critical way to usher in the next generation of physician scientists," said Hancock. "Our partnership with the ASN Foundation for Kidney Research demonstrates our collaborative efforts to solve the critical need in nephrology research that we believe will move us toward therapies for PKD."

With its contribution, the PKD Foundation becomes the sixth member of the ASN Foundation Founders Circle, joining Fresenius Medical Care, ASN, the American Renal Patient Care Foundation, Inc., Amgen and Baxter.

Read the full story

Friday, October 30, 2015 9:51:00 AM

Mini-kidney organoids re-create disease in a lab dish

Stem-cell biology and gene editing advances offer hope for kidney regeneration, drug discovery

Mini-kidney organoids have now been grown in a laboratory to re-recreate human kidney disease in a petri dish. The achievement, believed to be the first of its kind, resulted from combining stem cell biology with leading-edge gene-editing techniques. The journal Nature Communications reported the findings Oct. 23, 2015.

Scientists at Brigham and Women's Hospital and Harvard Medical School in the Boston and UW Medicine in Seattle collaborated on the work.

The mini-kidney organoids were grown from pluripotent stem cells. These are human cells that have turned back the clock to a time when they could develop into any type of organ in the body. When treated with a chemical cocktail, these stem cells matured into structures that resemble miniature kidneys. These organoids contain tubules, filtering cells and blood vessel cells. They transport chemicals and respond to toxic injury in ways that are similar to kidney tubules in people.

"A major unanswered question was whether we could re-create human kidney disease in a lab petri dish using this technology," said Benjamin Freedman, who led the studies at Brigham and Women's Hospital. He is now an assistant professor of medicine in the Division of Nephrology at the University of Washington and a UW Medicine researcher.

Read more

Friday, October 23, 2015 11:35:00 AM

Voices of PKD

Do You Know PKD?

New Orleans Saintsations Kriste Lewis, along with others impacted by PKD, helps create awareness in this promotional video. Please help spread the word to people who may not know about this disease by sharing this video.

Do You Know PKD?