Research GrantsResearch Grants

The PKD Foundation is funding 15 research projects selected for their promise in developing new strategies to treat ADPKD and ARPKD. The PKD Foundation will spend nearly $2.4 million over two years on these grants through the Research Grant Program.

 

After the first year of funding, we ask for updates on the progress of this research. The results reported are representative of one year of progress and are subject to change as the research progresses toward its stated goals. We are excited the results to date highlight the diversity of this research and the promising directions it has already taken.

 

Read a summary of each grant's progress report
For summaries of the projects grant recipients are conducting, please click here or read below.

 

Dr. Vincent H. Gattone Research Award for the Top-Rated Grant Proposal
Funded by The Carlo and Micol Schejola Foundation

Advancing HSP90 Inhibitors Towards Clinical Trials for ADPKD

Dr. Erica GolemisErica Golemis, Ph.D.
The Research Institute of Fox Chase Cancer Center
(Therapy Development)

View Summary


International Awardees

The Eileen Creamer O'Neill Award

Targeting Glucose Metabolism in PKD: A Preclinical Proof-of-Concept Study*

Dr. Alessandra BolettaAlessandra Boletta, Ph.D.
Fondazione Centro San Raffaele
(Therapy Development)

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Health Care Utilization and Costs of ADPKD

Dr. York PeiYork Pei, M.D.
University of Toronto General Hospital
 

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Effects of Genetic and Pharmacological Ablation (Deletion) of KCNN4 on Disease Progression in Two Orthologous Mouse Models of PKD

Dr. Marie TrudelMarie Trudel, Ph.D.
Institut de Recherches Cliniques de Montreal
(Therapy Development)

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United States Awardees

The Jean A. Bost Award

Role of CFTR and NKCC1 in PKD

Dr. Jim CalvetJames Calvet, Ph.D.
University of Kansas Medical Center
(Discovery Research)

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The Haggard Family Award

Preclinical Assessment of MCP-1/CCR2 Inhibition as Treatment for ADPKD

Dr. Timothy Fields and Dr. Katherine Swenson-FieldsTimothy Fields, M.D., Ph.D., and Katherine Swenson-Fields, Ph.D.
University of Kansas Medical Center
(Therapy Development)

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Funded in Partnership with Friends and Family of Infant Sophie St. Aubin

Investigation of the Biological Basis and Therapeutic Effect of Anti-tumor Drug 11beta-dichloro on PKD*

Dr. Rachel GallagherAnna Rachel Gallagher, Ph.D.
Yale University
(Therapy Development)

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The Mrs. Pamela Whitcomb Larsen Award

The Role of Beta-catenin as Signal Integrator in PKD

Dr. Jordan KreidbergJordan Kreidberg, M.D., Ph.D.
Boston Children's Hospital
(Discovery Research)

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Role of Tulp3 and the Hedgehog Pathway in PKD

Dr. Karel Liem, Jr.Karel Liem, Jr., M.D., Ph.D.
Yale University
(Discovery Research)

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The Effects of Genetic Reactivation of Functional Polycystins on Progression of PKD*

ResearchMing Ma, Ph.D.
Yale University
(Discovery Research)

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Funded in partnership with KidneyTexas, Inc.

Role of miR-17~92 in the Pathogenesis of PKD

Dr. Vishal PatelVishal Patel, M.D.
University of Texas Southwestern Medical Center
(Discovery Research)

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Unifying Cystogenic Mechanism of ADPKD and ARPKD*

Dr, Feng QianFeng Qian, Ph.D.
University of Maryland Medical Center: Division of Nephrology
(Discovery Research)

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HDAC Inhibitor Mediated Kidney Cyst Reduction

Dr. Zhaoxia SunZhaoxia Sun, Ph.D.
Yale University
(Discovery Research)

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The Rosemary M. Peppet Award

Phosphodiesterase/cAMP Signaling in Renal Cystogenesis (Cyst Formation) in Zebrafish

Dr. Caroline SussmanCaroline Sussman, Ph.D.
Mayo Clinic
(Discovery Research)

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The Dan Larson Research Grant

In Vivo Analysis of Cilia Mechanosensation in the Kidney

Dr. Brad YoderBradley Yoder, Ph.D.
University of Alabama at Birmingham
(Discovery Research)

View Summary


Rachel GallagherRead what the PKD Foundation research grant does for Dr. Rachel Gallagher's work to end PKD.

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©2015, PKD Foundation ·The PKD Foundation is a 501 (c)(3), 509 (a)(1) public charity.

©2015, PKD Foundation ·The PKD Foundation is a 501 (c)(3), 509 (a)(1) public charity.