Potential Treatments

Learn about a few drugs not yet in the clinical trial stage but are being tested in animal models. Heard of roscovitine, triptolide? Learn more about these and other potential treatments.

Plx5568: A Phase II clinical trial is planned by Roche for this drug made by Plexikkon that has been shown to block cell proliferation in pre-clinical testing. Phase I studies evaluating the drug’s safety, dosage and side effects in healthy volunteers has been completed.
Roscovitine is a drug that blocks cell proliferation and is currently being tested in cancer trials and pre-clinical studies for PKD in cystic mice.
Pioglitazone is a drug that blocks cell proliferation and is being tested in pre-clinical studies for PKD in cystic mice.
Reversin is a drug that has been shown to restore kidney function in advanced cystic disease in pre-clinical studies.
Stem cells from human embryos are being tested as a means to restore kidney function in pre-clinical studies for PKD in cystic mice.

An Intro to PKD Research