Lixivaptan granted orphan drug status for ADPKD

An investigational drug being developed for the treatment of autosomal dominant polycystic kidney disease (ADPKD) has received orphan drug designation by the U.S. Food and Drug Administration (FDA). Lixivaptan is a potent, selective vasopressin V2 receptor antagonist...

Washington Summary September 2017

Big Budget Picture Congress has a busy fall schedule. The major proposals include approving spending for FY18, ensuring that federal debts are paid, dealing with immigration, and reducing certain taxes. Congress also may try to change or improve certain parts of the...

Research Update from Peter Harris, Ph.D., Mayo Clinic

Advances in Gene Editing; Implications for PKD Presently, treatment options in ADPKD focus on addressing changes in cellular pathways, such as increased proliferation or altered secretion that are thought to promote cystic expansion. However, theoretically in a simple...

Washington Summary August 2017

Health Care Reform In the early morning of July 28, the Senate failed to approve any changes to the Affordable Care Act (ACA or Obamacare). Majority Leader Mitch McConnell (R-KY) pulled the ACA repeal/replace bill from the legislative calendar for now. During its...

Washington Summary July 2017

Health Care Reform The Senate will not take up its most recent version of a bill (the BCRA) to replace the Affordable Care Act (ACA or Obamacare).  Senate Majority Leader Mitch McConnell (R-KY) has asked the Senate to vote on a proposal to repeal the ACA immediately...