A to Z definitions
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The zebrafish is a simple model for studying vertebrate development and genetics and is a means of understanding how not only fish, but all vertebrates including humans, develop from the moment that sperm fertilizes an egg.
Urine collection (24-hour)
A test done in combination with the blood creatinine test to determine kidney function, called creatinine clearance and is an approximation of glomerular filtration rate (GFR).
Angiotensin converting enzyme (ACE) inhibitors; a group of drugs commonly used to treat hypertension in PKD patients.
Autosomal dominant polycystic kidney disease (ADPKD)
Autosomal dominant polycystic kidney disease; the more common form of PKD, it occurs in approx. 1 in 500 live births.
A hormone that causes the body to retain salt and lose potassium.
A test used in prenatal diagnosis of chromosomal abnormalities in which a small amount of amniotic fluid, which contains fetal tissues, is sampled from the amniotic sac surrounding a developing fetus, and the fetal DNA is examined for genetic abnormalities.
The protective fluid contained in the amniotic sac of a pregnant female; the fluid is partially supplied by fetal urine which is produced by the fetal kidneys; in ARPKD, poor prenatal renal function causes a reduction in this fluid.
An outpouching in a blood vessel which can leak or rupture.
Procedures that utilize contrast dye injected into the blood vessels in order to clearly visualize them; it is typically used when an aneurysm is suspected or to look for blockages in heart vessels.
A powerful constrictor of blood vessels; it stimulates the production of aldosterone.