Clinical studies

For drugs and therapies to be developed for PKD, clinical studies must be conducted. Patients play a key role in the research and development process by volunteering to participate in clinical studies. From observational studies to clinical trials, you can help researchers unlock the secrets of PKD and find a treatment by participating in a study.

List of available clinical studies

A Clinical Trial of Water Therapy for ADPKD
A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases
A Randomised Feasibility Trial of High Water Intake in Polycystic Kidney Disease
A Safety, Pharmacokinetic, Single Ascending Dose Study of Tesevatinib in Pediatric Subjects With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
A Study Measuring Quality of Life, Treatment Preference and Satisfaction of ADPKD Patients in Europe
A Trial of Bardoxolone Methyl in Patients with ADPKD (FALCON)
ADPKD Alterations in Hepatic Transporter Function
ADPKD Registry for Patients
ADPKD Somatic Mutation Biorepository
An international multicenter registry study on autosomal recessive polycystic kidney disease (ARPKD) – ARegPKD
Analysis of Clinical and Molecular Genetic Data Influencing the Evolution and Response to Therapy of ADPKD Patients (Autosomal Dominant Polycystic Kidney Disease)
ARPKD and ARPKD-Related Diseases Database
Assessing a Dose‐Response Relationship of Hydralazine and Its Effects on DNA Methyltransferase 1 in Polycystic Kidney Disease Patients
Assessment of longitudinal changes in endothelial function and oxidative stress in normotensive patients with ADPKD
Canadian Medical Assessment of JINARC™ Outcomes Registry
Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD (GeneQuest)
Clinical and Molecular Investigations Into Ciliopathies
Clinical Care of Autosomal Polycystic Kidney Disease: Retrospective Analysis and Prospective PKD Genotyping (ADPKD)
Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults With ADPKD
Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease
Development and Assessment of The Polycystic Liver Disease Questionnaire (PLD-Q)
Dynamic Measurement of Renal Functional Reserve as a Predictor of Long-Term Renal Function
Efficacy of Tolvaptan on ADPKD Patients
ELiSA, a Study of Lixivaptan in Subjects with ADPKD
Feasibility Study of Metformin Therapy in ADPKD
Foam Sclerotherapy for the Treatment of Symptomatic Kidney or Liver Cysts in Patients with AD Polycystic Kidney and Liver Disease
FREEDOM-1: clinical study for living donor kidney transplant recipients
Genetics of Brain Aneurysm Formation in Autosomal Dominant Polycystic Kidney Disease
Lanreotide in Polycystic Kidney Disease Study (LIPS)
Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease (TAME)
Novel Imaging in ARPKD
Novel MRI Techniques to Evaluate ARPKD Kidney and Liver Disease Progression
Phase 3 Study of Lixivaptan in ADPKD
Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2)
PKD Biomarkers Repository Study
PKD Clinical and Translational Core Study (PKD Core)
Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD
Prospective PKD Genotyping
Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease (RAP)
Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease (ALERT)
Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD
Samsca PMS in ADPKD Patients
Statin Therapy in Patients with Early Stage ADPKD
Tesevatinib in Subjects With ADPKD
The German ADPKD Tolvaptan Treatment Registry
Tolvaptan-Octreotide LAR Combination in ADPKD
Using Preimplantation Genetic Diagnosis in Autosomal Dominant Polycystic Kidney Disease Patients: a Multicenter Clinical Trial
Venglustat Treatment for ADPKD (STAGED-PKD)