Kaplan Award

Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease

The Lillian Jean Kaplan International Prize for Advancement recognizes an individual(s) whose seminal scientific work constitutes tangible achievement toward improving knowledge and treatment of PKD. More than one prize may be awarded, and it may be awarded to residents of any country without restriction.

Award-winners 2022

Alessandra Boletta, Ph.D.

Alessandra Boletta, Ph.D.

Head of Research Unit, San Raffaele Scientific Institute

 

Dr. Boletta graduated in Biology from the University of Pavia, Italy. She carried out her doctorate-equivalent training at the Mario Negri Institute in Bergamo, Italy, working on gene delivery to the kidney. She went to Johns Hopkins University, USA, for her postdoctoral training. Here, she began her scientific activity on Polycystic Kidney Disease, working on heterologous expression of Polycystin-1 aimed at establishing cellular models to investigate the Polycystins function.

With support from a Telethon Career Program and a Marie Curie Excellence Award, Dr. Boletta moved back to Italy to establish her lab at the San Raffaele Scientific Institute in Milan. Here, she took on the position of Director for the Division of Genetics and Cell Biology (2014-2019), and she is currently Head of the Research Unit. Over the years, her lab has developed several cellular and animal models to study Polycystins function and the pathophysiology of ADPKD. Her laboratory has identified metabolic reprogramming as an important feature of the disease, offering several new options for therapy as well as novel insights into the pathogenesis of ADPKD. Dr. Boletta currently serves on the PKD Foundation Scientific Advisory Committee.

Albert Chee Meng Ong, B.M.B.Ch., M.A., D.M., F.R.C.P.

Albert Chee Meng Ong, B.M.B.Ch., M.A., D.M., F.R.C.P.

Professor of Renal Medicine, Head of Academic Nephrology, and Deputy Director for Clinical Academic Training at the University of Sheffield

 

Dr. Albert Ong is Professor of Renal Medicine at the University of Sheffield and a consultant nephrologist at the Sheffield Kidney Institute, UK. Born in Malaysia, he graduated from the University of Oxford with degrees in physiological sciences, clinical medicine and a doctorate in renal cell biology. Following a lectureship at University College London (UCL), he was awarded a Kidney Research UK Senior Research Fellowship in genetics at Oxford (Harris lab, Weatherall Institute of Molecular Medicine), where he began working on the genetics and cell biology of ADPKD. After joining the University of Sheffield, he established a new research program in ADPKD, supported initially by a Wellcome Trust Research Leave Award.

The major aim of his laboratory over the past 20 years has been to investigate the molecular basis of cyst formation, in particular, the functions of the ADPKD proteins, polycystin-1, and polycystin-2, in cyst initiation. The focus of clinical and translational research has been to identify genetic and non-genetic factors influencing variability in disease expression, test novel treatments and introduce innovations to improve patient care. His international leadership roles have included OVERTURE, STAGED-PKD, SONG-PKD, KDIGO-PKD, EAF and CYSTIC. He currently serves as a member of the ERA Council and the ISN Fellowship Committee.

Nominations for 2023

Nominations for the 2023 award are due August 27, 2022. 

Award presentation to be held at: ISN WCN 2023, March 30- April 02 in Beijing, China

Nomination requirements:

  • Your details: complete name, ISN membership number, and contact information
  • Nominee details: complete name (as listed in publications) and contact information
  • Support statement: a description of how and why the nominee’s work represents a major advance in basic or clinical understanding of PKD, distinguishing those aspects which clearly set it apart from the work of others in the field, and a summary of the nominee’s contributions
  • Full curriculum vitae and bibliography of the nominee
  • Letters of support: at least two

All nominations and supporting materials are to be sent via email to Jo-Ann Donner at jdonner@theisn.org.

Winners are selected by the Lillian Jean Kaplan Prize Advisory Committee: Committee Chair Dr. Nathan Levin, two committee members selected by the PKD Foundation, and two ISN members.

Past award recipients

2021

Kyongtae (Ty) Bae, M.D., Ph.D., M.B.A.

Kyongtae (Ty) Bae, M.D., Ph.D., M.B.A.

University of Pittsburgh

Pittsburgh, PA

2020

Arlene Chapman, M.D.

Arlene Chapman, M.D.

University of Chicago

Chicago

2019

York Pei, M.D.

York Pei, M.D.

University of Toronto

Canada

Bradley Yoder, Ph.D.

Bradley Yoder, Ph.D.

University of Alabama at Birmingham

Birmingham, Ala.

2017

Ronald D. Perrone, M.D.

Ronald D. Perrone, M.D.

Tufts Medical Center

Boston

David R. Beier, M.D., Ph.D.

David R. Beier, M.D., Ph.D.

Seattle Children’s Research

Seattle

2015

Peter Igarashi, M.D.

Peter Igarashi, M.D.

University of Minnesota Medical School

Minneapolis

Gregory J. Pazour, Ph.D.

Gregory J. Pazour, Ph.D.

University of Massachussetts Medical School

Worcester, Mass.

2013

Vincent Gattone, Ph.D.

Vincent Gattone, Ph.D.

Indiana University School of Medicine

Indianapolis

Dorien Peters, Ph.D.

Dorien Peters, Ph.D.

Leiden University Medical Center

Leiden, Netherlands

2011

Gerd Walz, M.D.

Gerd Walz, M.D.

Freiburg Medical Center

Germany

James Calvet, Ph.D.

James Calvet, Ph.D.

University of Kansas Medical Center

Kansas City, Kan.

2009

Lisa Guay-Woodford, M.D.

Lisa Guay-Woodford, M.D.

University of Alabama at Birmingham

Birmingham, Ala.

Corinne Antignac, M.D., Ph.D.

Corinne Antignac, M.D., Ph.D.

Necker Hospital

Paris

Friedhelm Hildebrandt, M.D.

Friedhelm Hildebrandt, M.D.

Harvard Medical School

Boston

2007

Jing Zhou, M.D., Ph.D.

Jing Zhou, M.D., Ph.D.

Harvard Medical Center

Boston

Vicente Torres, M.D.

Vicente Torres, M.D.

Mayo Clinic

Rochester, Minn.

2005

Greg Germino, M.D.

Greg Germino, M.D.

Johns Hopkins University School of Medicine

Baltimore

Stefan Somlo, M.D.

Stefan Somlo, M.D.

Yale University School of Medicine

New Haven, Conn.

2003

Jared J. Grantham, M.D.

Jared J. Grantham, M.D.

University of Kansas Medical Center

Kansas City, Kan.

Peter Harris, Ph.D.

Peter Harris, Ph.D.

Mayo Clinic

Rochester, Minn.

Page last edited February 2022

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